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What is vigabatrin?

2025-11-29 22:51:29 healthy

What is vigabatrin?

Vigabatrin is an anti-epileptic drug used to treat epilepsy and infantile spasms. It reduces the frequency of epileptic seizures by inhibiting the degradation of gamma-aminobutyric acid (GABA) and increasing the concentration of GABA in the brain. In recent years, vigabatrin has become one of the hot topics of concern to the medical community and patients due to its unique pharmacological effects and clinical applications.

1. Basic information about vigabatrin

What is vigabatrin?

Drug nameVigabatrin
Product nameSabril
IndicationsEpilepsy, infantile spasms
Pharmacological effectsInhibit GABA degradation and increase brain GABA concentration
Common dosage formsTablets, oral solution

2. Clinical application of vigabatrin

Vigabatrin is mainly used to treat the following diseases:

disease typeApplicable peopleCurative effect
Intractable epilepsyadults and childrenReduce frequency of epileptic seizures
infantile spasmsbabyImprove spasm symptoms

3. Side effects and precautions of vigabatrin

Although vigabatrin is effective in treating epilepsy, its side effects cannot be ignored. The following are common side effects and precautions:

side effectsincidenceCountermeasures
visual impairmenthigherRegular eye exams
LethargycommonAvoid driving or operating machinery
weight gaincommonControl your diet and exercise appropriately

4. Contraindications for the use of vigabatrin

Vigabatrin is not suitable for all people and should be disabled or used with caution in the following situations:

Taboo groupsReason
pregnant womanMay affect the fetus
Severe liver insufficiencyImpaired drug metabolism
People allergic to vigabatrinMay cause allergic reactions

5. Market status and hot discussions of vigabatrin acid

In recent years, vigabatrin has become a hot topic in the medical field due to its unique pharmacological mechanism and clinical effects. The following is the hot discussion content in the past 10 days:

hot topicsfocus of discussion
The use of vigabatrin in infantile spasmsEfficacy and Safety Assessment
Risk of vision impairment with vigabatrinHow to reduce side effects
Vigabatrin compared with other antiepileptic drugsEfficacy and cost analysis

6. Summary

Vigabatrin is an important antiepileptic drug, particularly effective in the treatment of refractory epilepsy and infantile spasms. However, its side effects (such as visual impairment) also require great attention. Patients should fully understand its indications, side effects and contraindications before use, and use the medication rationally under the guidance of a doctor. In the future, with the deepening of medical research, the clinical application prospects of vigabatrin will be broader.

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